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These soft, bite-sized chews promote calmness, relaxation, and mood balance so your dog can live a happy, stress-free life.

Powerful, Calming Blend

Our Anxiety Chews are the ideal supplement to help ease dogs' stress, anxiety, and anger and promote relaxation in overly tense dogs. Crafted with various natural calming ingredients, our chew helps promote mood balance and relaxation, while maintaining mental alertness and cognitive function. These chews are perfect for those looking to help their dog deal with separation anxiety and combat the negative behaviors that often come along with it. [4,5,10,11]

Not Your Average Anxiety Chew

We formulated our Anxiety Chew to include Hemp Seed Oil so your pup can experience overall wellness benefits. Rich in vitamins and minerals, Hemp Seed Oil has natural anti-inflammatory properties that may help ease inflammation in response to injuries, infections, allergies, and other ailments. [1,12]

Duck Flavored Chews

Often other chews and tablets are unpalatable and an unenjoyable experience for your dog. Our chews have undergone rigorous taste testing across all breeds to find the perfect blend of flavors so that your pooch will enjoy them and keep coming back for more!

Organic Chamomile

Chamomile is an herbal supplement that has been used due to its medicinal properties for centuries. Its effects come from natural plant compounds called terpenoids and flavonoids. Evidence shows that chamomile may ease your pup’s mood, as well as other benefits.

Helps ease mild anxiety and stress

Acts as a natural muscle relaxant

May help ease nervous upset stomachs

Dogs that exhibit restless, nervous, and hyperactive behaviors can especially benefit from this herbal ingredient.^3,4,5

Small black, white, and brown dog sitting

Valerian Root

Valerian root is a natural herb that has been said to block nerve transmissions in the brain that stimulate activity. Therefore, it has a calming effect on the brain.

Helps reduce stress and anxiety

Boosts sleep quality

Aids in reducing hyperactivity and restlessness

Valerian root can help calm your canine and combat fears your dog may have, such as separation anxiety and unfamiliar situations.⁶

Organic Passion Flower

This perennial vine is known for its calming abilities and has been used for many years for medicinal purposes. Passionflower is now widely used as a calming remedy that helps to relax your dog’s mind, body, and even stomach.

Helps reduce fear and separation anxiety

Boosts mood and temperament

Supports brain function

It is a natural remedy that can work wonders for your dog as it lowers brain cell activity, helping your dog be in a calm and relaxed state.^7,8,9

L-Theanine

This amino acid has been shown to have a positive effect on reducing anxiety and nervousness in dogs. L-theanine helps promote relaxation, which can be linked to lower blood pressure, as well as improved cognitive function and mood.

Promotes healthy sleep

Supports a relaxed, yet alert mental state

Boosts levels of dopamine and GABA

Since this natural amino acid has a calming effect, your pup may be less susceptible to displaying aggressive or destructive behavior.^10,11

Additional Ingredients

Cane Molasses, Chickpea Flour, Dried Brewer’s Yeast, Mixed Tocopherols, Natural Flavor, Porcine Plasma Powder, Potato Flour, Powdered Turkey Cooked, Purified Water, Safflower Oil, Sunflower Lecithin, Tapioca Starch, Vegetable Glycerin.

These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease or health condition.

Callaway, James, et al. Efficacy of dietary hempseed oil in patients with atopic dermatitis. Jour Dermatological Treatment. 2005. 16: 87-94. https://pubmed.ncbi.nlm.nih.gov/16019622/
Zurier, Robert B, et al. Gamma-Linolenic Acid Treatment Of Rheumatoid Arthritis. Arthritis & Rheumatism. 1996. Vol. 39, No. 11. Pp 1808-1817. https://pubmed.ncbi.nlm.nih.gov/8912502/
Gollakner, R. (n.d.). Chamomile: VCA Animal Hospitals. VCA Animal Hospitals. Retrieved April 6, 2023, from https://vcahospitals.com/know-your-pet/chamomile
Srivastava, J. K., Shankar, E., & Gupta, S. (2010). Chamomile: A herbal medicine of the past with bright future. Molecular medicine reports, 3(6), 895–901. https://doi.org/10.3892/mmr.2010.377
Taylor, S., & Madden, J. (2016). The Effect of Pet Remedy on the Behaviour of the Domestic Dog (Canis familiaris). Animals : an open access journal from MDPI, 6(11), 64. https://doi.org/10.3390/ani6110064
PetMD. (2017, August 16). Valerian root for dogs: Does it work? PetMD. Retrieved April 6, 2023, from https://www.petmd.com/dog/wellness/valerian-root-dogs-does-it-work
Akhondzadeh S, Naghavi HR, Vazirian M, Shayeganpour A, Rashidi H, Khani M. Passionflower in the treatment of generalized anxiety: a pilot double-blind randomized controlled trial with oxazepam. J Clin Pharm Ther. 2001;26(5):369-373. https://pubmed.ncbi.nlm.nih.gov/11679026/
Barbosa PR, Valvassori SS, Bordignon CL Jr, Kappel VD, Martins MR, Gavioli EC, et al. The aqueous extracts of Passiflora alata and Passiflora edulis reduce anxiety-related behaviors without affecting memory process in rats. J Med Food. 2008 Jun;11(2):282-8. https://pubmed.ncbi.nlm.nih.gov/18598170/
Elsas SM, Rossi DJ, Raber J, White G, Seeley CA, Gregory WL, Mohr C, Pfankuch T, Soumyanath A. Passiflora incarnata L. (Passionflower) extracts elicit GABA currents in hippocampal neurons in vitro, and show anxiogenic and anticonvulsant effects in vivo, varying with extraction method. Phytomedicine. 2010;17(12):940-9. https://pubmed.ncbi.nlm.nih.gov/20382514/
Gollakner, R. (n.d.). Chamomile: VCA Animal Hospitals. VCA Animal Hospitals. Retrieved April 6, 2023, from https://vcahospitals.com/know-your-pet/chamomile
Srivastava, J. K., Shankar, E., & Gupta, S. (2010). Chamomile: A herbal medicine of the past with bright future. Molecular medicine reports, 3(6), 895–901. https://doi.org/10.3892/mmr.2010.377
Taylor, S., & Madden, J. (2016). The Effect of Pet Remedy on the Behaviour of the Domestic Dog (Canis familiaris). Animals : an open access journal from MDPI, 6(11), 64. https://doi.org/10.3390/ani6110064

Product FAQ

What is this supplement for? Does it have the correct dosage for my dog’s needs?
PupGrade Anxiety Chews is a chewable supplement for dogs and puppies of all breeds, sizes, ages, and activity levels. Suitable for everyday canine health.
Our Anxiety Chew is a research-backed formula with just the right amount of essential nutrients to help provide anxiety and stress support for your dog.
How do I feed this supplement to my dog?
We recommend following these directions for use:
- 1 Chew: per 25 lbs.
- Extra Support: double dosage first 4 weeks.
- >1 Chew Daily: divide between AM & PM.
*This product is intended for intermittent or supplemental feeding only.
Is this supplement free of grain?
We are a veterinarian-formulated brand you can trust. These chews are made with only the good stuff and are 100% junk free! We are proud to offer your pet savory, GMP-Certified chews free of grains, wheat, corn, artificial colors, dyes, or harmful preservatives.
How many chews are in this container?
Our Anxiety Chew supplements offer 60 chews per container.
What are the ingredients included in this product?
Active Ingredients: Hemp Seed Oil, Organic Chamomile, Valerian Root, Organic Passion Flower, L-Theanine, Organic Ginger Powder, Ashwagandha Root Powder, Magnesium Gluconate, L-Tryptophan, and Melatonin.
Other Ingredients: Cane Molasses, Chickpea Flour, Dried Brewer’s Yeast, Mixed Tocopherols, Natural Flavor, Porcine Plasma Powder, Potato Flour, Powdered Turkey Cooked, Purified Water, Safflower Oil, Sunflower Lecithin, Tapioca Starch, Vegetable Glycerin.
What is the Guaranteed Analysis per chew (4g)?
- Calories per chew: 15 Kcal
- Crude Protein: NLT 12%
- Crude Fat: NLT 17%
- Crude Fiber: NMT 8%
- Moisture: NMT 10%
Are these chews safe for my dog if they have sensitivities or other conditions?
We understand that every dog has unique needs. That’s why we offer supplements tailored to address specific concerns, such as sensitive stomachs and diabetic conditions. Our supplements contain easily digestible ingredients and exclude common allergens.
How do I store this product?
Store in a cool, dry place. Ensure container lid is securely closed after each use.

A Happy, Calm Canine Means a Happy, Healthy Life

PupGrade Anxiety Chews are formulated to promote calmness and provide support for normal stress and separation anxiety. Our herbal and natural ingredients help support relaxation, all while maintaining mental alertness. As with any of our PupGrade products, we tested our formula extensively to ensure our Anxiety Chews are the best source and dosage of important ingredients your dog needs to live a happy, healthy, and calm life. And they taste amazing, too!

Image of PupGrade Anxiety Chews 60 count jar on a white background.

Calm Your Dog's Anxiety Naturally

See The Difference With PupGrade’s Anxiety Chews

Say goodbye to stress and anxiety in your furry friend—our natural chews are made with a blend of calming herbs and L-Theanine, so you can be sure your dog will feel relaxed and happy. Plus, they're delicious, so your pup will love the taste. Give your furry friend the gift of peace of mind with PupGrade Anxiety Chews!

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